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Article

Genotypic Diversity within a Single Pseudomonas aeruginosa Strain Commonly Shared by Australian Patients with Cystic Fibrosis.

PloS one - 1 Jan 2015

Tai Anna Sze, Bell Scott Cameron, Kidd Timothy James, Trembizki Ella, Buckley Cameron, Ramsay Kay Annette, David Michael, Wainwright Claire Elizabeth, Grimwood Keith, Whiley David Mark

Abstract excerpt

In cystic fibrosis (CF), Pseudomonas aeruginosa undergoes intra-strain genotypic and phenotypic diversification while establishing and maintaining chronic lung infections. As the clinical significance of these changes is uncertain, we investigated intra-strain diversity in commonly shared strains from CF patients to determine if specific gene mutations were associated with increased antibiotic resistance and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26633539
DOI: 10.1371/journal.pone.0144022
PMCID: PMC4669131

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