Article
An assessment of the impact of pharmacogenomics on health disparities: a systematic literature review.
Pharmacogenomics - 1 Nov 2017
Martin Antony, Downing Jennifer, Maden Michelle, Fleeman Nigel, Alfirevic Ana, Haycox Alan, Pirmohamed Munir
Abstract excerpt
This review assessed evidence of disparities in benefits of pharmacogenomics related to 'model performance' in subgroups of patients and studies which reported impact on health inequalities. 'Model performance' refers to the ability of algorithms including clinical, environmental and genetic information to guide treatment. A total of 4978 abstracts were screened by one reviewer and 30% (1494) were double screened...
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