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Article

Identification of a Critical and Conformational Neutralizing Epitope in Human Adenovirus Type 4 Hexon.

Journal of virology - 15 Jan 2018

Tian Xingui, Qiu Hongling, Zhou Zhichao, Wang Shouli, Fan Ye, Li Xiao, Chu Ruiai, Li Haitao, Zhou Rong, Wang Hui

Abstract excerpt

Human adenovirus type 4 (HAdV-4) is an epidemic virus that contributes to serious acute respiratory disease (ARD) in both pediatric and adult patients. However, no licensed drug or vaccine is currently available to the civilian population. The identification of neutralizing epitopes of HAdV-4 should allow the development of a novel antiviral vaccine and a novel gene transfer vector, and an effective neutralizing...

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Share to Adenovirus Infections, Human
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29093098
DOI: 10.1128/JVI.01643-17
PMCID: PMC5752955

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