Article
Antigenic variability among two subtypes of human adenovirus serotype 7.
Virus genes - 1 Aug 2014
Tian Xingui, Su Xiaobo, Xue Chunyan, Li Xiao, Zhou Zhichao, Zhou Rong
Abstract excerpt
Human adenovirus type 7 (HAdV-7) is one of the major serotypes responsible for acute respiratory infection. It is important to investigate the antigenic variabilities of different HAdV-7 genomic subtypes for vaccine development. Phylogenetic analysis of global HAdV-7 strains and major antigen proteins showed that HAdV-7 could be classified into two subtypes. There were three highly variable regions (HVR1, HVR4,...
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