Non-antibiotic antimicrobial triclosan induces multiple antibiotic resistance through genetic mutation.

doi:10.1016/j.envint.2018.06.004

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Article

Non-antibiotic antimicrobial triclosan induces multiple antibiotic resistance through genetic mutation.

Environment international - 1 Sept 2018

Lu Ji, Jin Min, Nguyen Son Hoang, Mao Likai, Li Jie, Coin Lachlan J M, Yuan Zhiguo, Guo Jianhua

Abstract excerpt

Antibiotic resistance poses a major threat to public health. Overuse and misuse of antibiotics are generally recognized as the key factors contributing to antibiotic resistance. However, whether non-antibiotic, anti-microbial (NAAM) chemicals can directly induce antibiotic resistance is unclear. We aim to investigate whether the exposure to a NAAM chemical triclosan (TCS) has an impact on inducing antibiotic...

Topics

Anti-Infective Agents
Drug Resistance, Bacterial
Escherichia coli
Mutation
Oxidative Stress
Triclosan

Source

Open in PubMed

Identifiers

PMID: 29902774
DOI: 10.1016/j.envint.2018.06.004

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