Article
Parallel evolutionary pathways to antibiotic resistance selected by biocide exposure.
The Journal of antimicrobial chemotherapy - 1 Aug 2015
Webber Mark A, Whitehead Rebekah N, Mount Manuella, Loman Nick J, Pallen Mark J, Piddock Laura J V
Abstract excerpt
OBJECTIVES: Biocides are widely used to prevent infection. We aimed to determine whether exposure of Salmonella to various biocides could act as a driver of antibiotic resistance. METHODS: Salmonella enterica serovar Typhimurium was exposed to four biocides with differing modes of action. Antibiotic-resistant mutants were selected during exposure to all biocides and characterized phenotypically and genotypically...
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