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Article

Modulation of the Senescence-Associated Inflammatory Phenotype in Human Fibroblasts by Olive Phenols.

International journal of molecular sciences - 30 Oct 2017

Menicacci Beatrice, Cipriani Caterina, Margheri Francesca, Mocali Alessandra, Giovannelli Lisa

Abstract excerpt

Senescent cells display an increase in the secretion of growth factors, inflammatory cytokines and proteolytic enzymes, termed the "senescence-associated-secretory-phenotype" (SASP), playing a major role in many age-related diseases. The phenolic compounds present in extra-virgin olive oil are inhibitors of oxidative damage and have been reported to play a protective role in inflammation-related diseases....

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Identifiers

PMID: 29084133
DOI: 10.3390/ijms18112275
PMCID: PMC5713245

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Modulation of the Senescence-Associated Inflammatory Phenotype in Human Fibroblasts by Olive Phenols.PMID 29084133Read ↗

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