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Article

Methyl caffeate and some plant constituents inhibit age-related inflammation: effects on senescence-associated secretory phenotype (SASP) formation.

Archives of pharmacal research - 1 Apr 2017

Lim Hyun, Park Byung Kyu, Shin Sook Young, Kwon Yong Soo, Kim Hyun Pyo

Abstract excerpt

During aging, cells secrete molecules called senescence-associated secretory phenotype (SASP). They constitute chronic low-grade inflammation environment to adjacent cells and tissues. In order to find inhibiting agents of SASP formation, 113 plant constituents were incubated with BJ fibroblasts for 6 days after treatment with bleomycin. Several plant constituents showed considerable inhibition of IL-6...

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Identifiers

PMID: 28299617
DOI: 10.1007/s12272-017-0909-y

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CXCL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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