Article
Association between lung cancer somatic mutations and occupational exposure in never-smokers.
The European respiratory journal - 1 Oct 2017
Paris Christophe, Do Pascal, Mastroianni Bénédicte, Dixmier Adrien, Dumont Patrick, Pichon Eric, Chouaid Christos, Coudert Bruno, Foucher Pascal, Fraboulet Séverine, Locatelli-Sanchez Myriam, Baize Nathalie, Dansin Eric, Moreau Lionel, Vincent Michel, Missy Pascale, Morin Franck, Moro-Sibilot Denis, Couraud Sébastien
Abstract excerpt
Occupational exposure constitutes a common risk factor for lung cancer. We observed molecular alterations in 73% of never-smokers, 35% of men and 8% of women were exposed to at least one occupational carcinogen. We report herein associations between molecular patterns and occupational exposure.BioCAST was a cohort study of lung cancer in never-smokers that reported risk factor exposure and molecular patterns....
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