Article
No impact of passive smoke on the somatic profile of lung cancers in never-smokers.
The European respiratory journal - 1 May 2015
Couraud Sébastien, Debieuvre Didier, Moreau Lionel, Dumont Patrick, Margery Jacques, Quoix Elisabeth, Duvert Bernard, Cellerin Laurent, Baize Nathalie, Taviot Bruno, Coudurier Marie, Cadranel Jacques, Missy Pascale, Morin Franck, Mornex Jean-François, Zalcman Gérard, Souquet Pierre-Jean
Abstract excerpt
EGFR and HER2 mutations and ALK rearrangement are known to be related to lung cancer in never-smokers, while KRAS, BRAF and PIK3CA mutations are typically observed among smokers. There is still debate surrounding whether never-smokers exposed to passive smoke exhibit a "smoker-like" somatic profile compared with unexposed never-smokers. Passive smoke exposure was assessed in the French BioCAST/IFCT-1002...
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