Article
Long exposure of environmental tobacco smoke associated with activating EGFR mutations in never-smokers with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2011
Kawaguchi Tomoya, Ando Masahiko, Kubo Akihito, Takada Minoru, Atagi Shinji, Okishio Kyoichi, Asami Kazuhiro, Matsumura Akihide, Tsujino Kazuyuki, Ignatius Ou Sai-Hong, Sasaki Hidefumi
Abstract excerpt
PURPOSE: To examine an association between environmental tobacco smoke (ETS) and activating epidermal growth factor receptor (EGFR) mutations in never-smokers with non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN: A total of 126 never-smokers with NSCLC were prospectively included in this study. Detailed ETS information was obtained through a standardized questionnaire including exposure period, place, and...
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