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Article

An ApiAP2 member regulates expression of clonally variant genes of the human malaria parasite Plasmodium falciparum.

Scientific reports - 25 Oct 2017

Martins Rafael M, Macpherson Cameron R, Claes Aurélie, Scheidig-Benatar Christine, Sakamoto Hiroshi, Yam Xue Yan, Preiser Peter, Goel Suchi, Wahlgren Mats, Sismeiro Odile, Coppée Jean-Yves, Scherf Artur

Abstract excerpt

Variegated surface antigen expression is key to chronic infection and pathogenesis of the human malaria parasite Plasmodium falciparum. This protozoan parasite expresses distinct surface molecules that are encoded by clonally variant gene families such as var, rif and stevor. The molecular mechanisms governing activation of individual members remain ill-defined. To investigate the molecular events of the initial...

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Identifiers

PMID: 29070841
DOI: 10.1038/s41598-017-12578-y
PMCID: PMC5656681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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