Article
Diagnostic utility of cortactin antibodies in myasthenia gravis.
Annals of the New York Academy of Sciences - 1 Jan 2018
Illa Isabel, Cortés-Vicente Elena, Martínez María Ángeles, Gallardo Eduard
Abstract excerpt
Patients with myasthenia gravis (MG) without antibodies to the acetylcholine receptor (AChR) or muscle-specific tyrosine kinase (MuSK) have been classified as having double-seronegative myasthenia gravis (dSNMG). We used the sera from six dSNMG patients with positive immunohistochemistry assays in a protein array to screen reactivity with 9000 human proteins. We identified cortactin, an intracellular protein that...
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