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Article

Establishment of a platform for molecular and immunological characterization of the RNA-dependent-RNA-polymerase NS5B of an Egyptian HCV isolate.

Journal of medical virology - 1 Mar 2018

Gewaid Hossam, Mesalam Ahmed A, Ibrahim Ahmed A, Abdel Shafy Dina N, Abdel Shafy Rola N, Emara Nahed, Hamdy Soha M, Gewaid Mohy, Bahgat Mahmoud M

Abstract excerpt

The present work aimed at establishing a platform to enable frequent characterization of the HCV RNA-dependent-RNA-polymerase from Egyptian clinical isolates. Subjecting amplified HCV-NS5B coding gene from Egyptian patient's serum to sequencing, multiple alignment, and phylogenetic analysis confirmed its subtype 4a origin. Nucleotide sequence analysis revealed presence of an additional start codon at the...

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PMID: 29064582
DOI: 10.1002/jmv.24977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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