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A branching process model of heterogeneous DNA damages caused by radiotherapy in in vitro cell cultures.

Mathematical biosciences - 1 Dec 2017

Bastogne T, Marchand J-L, Pinel S, Vallois P

Abstract excerpt

This paper deals with the dynamic modeling and simulation of cell damage heterogeneity and associated mutant cell phenotypes in the therapeutic responses of cancer cell populations submitted to a radiotherapy session during in vitro assays. Each cell is described by a finite number of phenotypic states with possible transitions between them. The population dynamics is then given by an age-dependent multi-type...

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PMID: 29054768
DOI: 10.1016/j.mbs.2017.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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