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Estimating Dose Painting Effects in Radiotherapy: A Mathematical Model

26 Feb 2014

Abstract excerpt

Tumor heterogeneity is widely considered to be a determinant factor in tumor progression and in particular in its recurrence after therapy. Unfortunately, current medical techniques are unable to deduce clinically relevant information about tumor heterogeneity by means of non-invasive methods. As a consequence, when radiotherapy is used as a treatment of choice, radiation dosimetries are prescribed under the...

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PMID: 24586734
DOI: 10.1371/journal.pone.0089380

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