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Article

A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants.

Pediatrics and neonatology - 1 Jun 2018

Ogasawara Kei, Sato Maki, Hashimoto Koichi, Imamura Takashi, Go Hayato, Hosoya Mitsuaki

Abstract excerpt

BACKGROUND: Glucocorticoids play an important role in endocrine control. The association of glucocorticoid receptor (GR) gene polymorphisms with altered sensitivity to glucocorticoid therapy has been reported in adults. However, there are few such reports in infants. The present study analyzed the prevalence of four GR polymorphisms in preterm infants born before 30 weeks of gestation and determined the...

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Identifiers

PMID: 29033349
DOI: 10.1016/j.pedneo.2017.04.007

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