Identification and replication of the interplay of four genetic high-risk variants for urinary bladder cancer.

doi:10.1093/carcin/bgx102

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Identification and replication of the interplay of four genetic high-risk variants for urinary bladder cancer.

Carcinogenesis - 7 Dec 2017

Selinski Silvia, Blaszkewicz Meinolf, Ickstadt Katja, Gerullis Holger, Otto Thomas, Roth Emanuel, Volkert Frank, Ovsiannikov Daniel, Moormann Oliver, Banfi Gergely, Nyirady Peter, Vermeulen Sita H, Garcia-Closas Montserrat, Figueroa Jonine D, Johnson Alison, Karagas Margaret R, Kogevinas Manolis, Malats Nuria, Schwenn Molly, Silverman Debra T, Koutros Stella, Rothman Nathaniel, Kiemeney Lambertus A, Hengstler Jan G, Golka Klaus

Abstract excerpt

Little is known whether genetic variants identified in genome-wide association studies interact to increase bladder cancer risk. Recently, we identified two- and three-variant combinations associated with a particular increase of bladder cancer risk in a urinary bladder cancer case-control series (Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), 1501 cases, 1565 controls)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Case-Control Studies

Share to Genome-Wide Association Study

Share to Odds Ratio

Share to Risk Factors

Share to Urinary Bladder Neoplasms

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29028944
DOI: 10.1093/carcin/bgx102
PMCID: PMC5862341

Genes

CBX6
CCNE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and replication of the interplay of four genetic high-risk variants for urinary bladder cancer.PMID 29028944Read ↗

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related riskSemantic proximity Read ↗

Genetic variants in urinary bladder cancer: collective power of the "wimp SNPs".Semantic proximity Read ↗

Distinct SNP combinations confer susceptibility to urinary bladder cancer in smokers and non-smokers.Semantic proximity Read ↗

Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights.Semantic proximity Read ↗

Diet quality, common genetic polymorphisms, and bladder cancer risk in a New England population-based study.Semantic proximity Read ↗

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.Semantic proximity Read ↗

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.Semantic proximity Read ↗

Genome-wide association study identifies multiple loci associated with bladder cancer risk.Semantic proximity Read ↗

Cumulative effect of genome-wide association study-identified genetic variants for bladder cancer.Semantic proximity Read ↗

ERCC1 haplotypes modify bladder cancer risk: a case-control study.Semantic proximity Read ↗

Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.Semantic proximity Read ↗

Genome-wide exploration of genetic interactions for bladder cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.