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Article

A Specialist Macaque MHC Class I Molecule with HLA-B*27-like Peptide-Binding Characteristics.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2017

de Groot Natasja G, Heijmans Corrine M C, de Ru Arnoud H, Janssen George M C, Drijfhout Jan W, Otting Nel, Vangenot Christelle, Doxiadis Gaby G M, Koning Frits, van Veelen Peter A, Bontrop Ronald E

Abstract excerpt

In different macaque species, the MHC A2*05 gene is present in abundance, and its gene products are characterized by low cell-surface expression and a highly conserved peptide-binding cleft. We have characterized the peptide-binding motif of Mamu-A2*05:01, and elucidated the binding capacity for virus-derived peptides. The macaque A2*05 allotype prefers the basic amino acid arginine at the second position of the...

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Identifiers

PMID: 29021373
DOI: 10.4049/jimmunol.1700502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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