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Article

Identify Huntington's disease associated genes based on restricted Boltzmann machine with RNA-seq data.

BMC bioinformatics - 11 Oct 2017

Jiang Xue, Zhang Han, Duan Feng, Quan Xiongwen

Abstract excerpt

BACKGROUND: Predicting disease-associated genes is helpful for understanding the molecular mechanisms during the disease progression. Since the pathological mechanisms of neurodegenerative diseases are very complex, traditional statistic-based methods are not suitable for identifying key genes related to the disease development. Recent studies have shown that the computational models with deep structure can learn...

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Identifiers

PMID: 29020921
DOI: 10.1186/s12859-017-1859-6
PMCID: PMC5637347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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