Article
MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1.
PloS one - 1 Jan 2017
Xie FeiYan, Hosany Sumayyah, Zhong Shen, Jiang Yang, Zhang Fen, Lin LiLi, Wang XiaoBo, Gao ShenMeng, Hu XiaoQu
Abstract excerpt
In many cancers, microRNA-193a (miR-193a) is a suppressor miRNA, but its underlying anti-oncogenic activity in breast cancer is not known. In this study, we found decreased miR-193a (specifically, miR-193a-5p) expression not only in breast cancer cell lines but also in breast cancer tissues as compared with the adjacent non-tumor tissues. Ectopic miR-193a overexpression inhibited the proliferation, colony...
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