Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFβ, and Wnt signaling

1 Mar 2019

Abstract excerpt

Liposarcoma is the most common soft tissue sarcoma. Molecularly targeted therapeutics have had limited efficacy in liposarcomas, in part because of inadequate knowledge of the complex molecular alterations in these tumors. Our recent study revealed the tumor suppressive function of miR-193b in liposarcoma. Considering the biological and clinical heterogeneity of liposarcoma, here, we confirmed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hippo pathway signaling and YAP/TAZ
Share to RNA Research and Splicing
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30824765
DOI: 10.1038/s41598-019-39560-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-193b regulates tumorigenesis in liposarcoma cells via PDGFR, TGFβ, and Wnt signalingPMID 30824765Read ↗

Liposarcoma: Advances in Cellular and Molecular Genetics Alterations and Corresponding Clinical TreatmentSemantic proximity Read ↗

Targeting liposarcoma: unveiling molecular pathways and therapeutic opportunitiesSemantic proximity Read ↗

Genetic, Epigenetic and Transcriptome Alterations in Liposarcoma for Target Therapy SelectionSemantic proximity Read ↗

FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitroSemantic proximity Read ↗

Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.Semantic proximity Read ↗

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma.Semantic proximity Read ↗

Clinical and Molecular Spectrum of LiposarcomaSemantic proximity Read ↗

Therapeutic opportunity of phosphodiesterase 3A modulators in myxoid liposarcomasSemantic proximity Read ↗

Liposarcoma: Molecular Genetics and TherapeuticsSemantic proximity Read ↗

Dysregulation of miRNAs in Soft Tissue SarcomasSemantic proximity Read ↗

Targeting MCM2 activates cancer-associated fibroblasts-like phenotype and affects chemo-resistance of liposarcoma cells against doxorubicin.Semantic proximity Read ↗

Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.