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Article

NDPKA is not just a metastasis suppressor - be aware of its metastasis-promoting role in neuroblastoma.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2018

Tan Choon-Yee, Chang Christina L

Abstract excerpt

NDPK-A, encoded by nm23-H1 (also known as NME1) was the first metastasis suppressor discovered. Much of the attention has been focused on the metastasis-suppressing role of NDPK-A in human tumors, including breast carcinoma and melanoma. However, compelling evidence points to a metastasis-promoting role of NDPK-A in certain tumors such as neuroblastoma and lymphoma. To balance attention on this contrariety of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28991262
DOI: 10.1038/labinvest.2017.105

Genes

NME1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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