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Article

Development and characterization of a human orthotopic neuroblastoma xenograft

11 Apr 2015

Abstract excerpt

Neuroblastoma is a pediatric cancer of the developing sympathoadrenal lineage. The tumors are known to develop from the adrenal gland or paraspinal ganglia and have molecular and cellular features of sympathetic neurons such as dense core vesicles and catecholamine production. Here we present the detailed molecular, cellular, genetic and epigenetic characterization of an orthotopic xenograft derived from a...

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PMID: 25863122
DOI: 10.1016/j.ydbio.2015.02.002

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