Article
[Hereditary cancer syndromes in gynecology: what the practitioner needs to know!].
Schweizerische medizinische Wochenschrift - 11 Mar 2000
Kuschel B, Köchli O R, Niederacher D, Müller H, Beckmann M W
Abstract excerpt
During the last 5 years progress in molecular genetics has offered the possibility of genetic testing for inherited mutations of cancer-predisposing genes. The exact cellular function and carcinogenic potential of these genes is yet not completely understood. Only in 5-20% of all cancers inherited genetic mutations play an important role in the polygenic and multifactorial nature of the disease. Identification of...
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