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Article

[Common and rare variants, polygenic traits and missing heritability].

Medecine sciences : M/S - 1 Jan 2000

Jordan Bertrand

Abstract excerpt

Recently, a systematic (but limited) search for rare variants implicated in adult height, a highly polygenic trait, has uncovered a number of new variants for which the effect size is inversely correlated with the minor allele frequency. This opens interesting perspectives on the genetic architecture of complex traits and on the vexing problem of "missing heritability".

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28990573
DOI: 10.1051/medsci/20173306028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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