Article
Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates.
Virus research - 2 Jan 2018
Islam Saimul, Mazumder Indra Dipanjana, Basu Mukta, Roychowdhury Anirban, Das Pijush, Dasgupta Hemantika, Roy Anup, Alam Neyaz, Mondal Ranajit Kumar, Roychoudhury Susanta, Panda Chinmay Kumar
Abstract excerpt
The genetic variations of HPV16 in Breast Cancer (BC) are not well studied unlike HPV16 in Cervical Cancer (CACX). In this study, the genetic variations of HPV16 in BC were compared with HPV16 in CACX. In sequencing analysis of LCR, E6 and E7 regions of HPV16 in BC and CACX the A lineage was seen to be 64.2% and 66.6% respectively. The other lineages showed differential frequency in BC and CACX. The mutation...
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