Article
Association Between Interleukin-10 Receptors and the CD45-Immunophenotype of Central Nervous System Tumors: A Preliminary Study.
Anticancer research - 1 Oct 2017
Zadka Lukasz, Kram Pawel, Koscinski Jeremi, Jankowski Roman, Kaczmarek Mariusz, Piatek Katarzyna, Kulus Michal, Gomułkiewicz Agnieszka, Piotrowska Aleksandra, Dziegiel Piotr
Abstract excerpt
BACKGROUND/AIM: One of the current hypotheses assumes that brain tumors exert an immunosuppressive influence on the surrounding cellular environment. Interleukin-10 (IL-10) is one of the immunosuppressive cytokines modifying the biological activity of cancer. The aim of this study was to assess the expression of IL10R in CD45+ cells within primary brain tumors and metastases and establish its association with...
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