Article
Estimating Allele Frequencies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Adrianto Indra, Montgomery Courtney
Abstract excerpt
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimators of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele frequencies. Factors that influence allele frequencies in...
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