Article
Inference of haplotypes from PCR-amplified samples of diploid populations.
Molecular biology and evolution - 1 Mar 1990
Clark A G
Abstract excerpt
Direct sequencing of genomic DNA from diploid individuals leads to ambiguities on sequencing gels whenever there is more than one mismatching site in the sequences of the two orthologous copies of a gene. While these ambiguities cannot be resolved from a single sample without resorting to other experimental methods (such as cloning in the traditional way), population samples may be useful for inferring...
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