Article
Pharmacogenomics of Bucindolol in Atrial Fibrillation and Heart Failure.
Current heart failure reports - 1 Dec 2017
Parikh Kishan S, Piccini Jonathan P
Abstract excerpt
PURPOSE OF REVIEW: We explore the pharmacogenomics of the beta-blocker bucindolol by discussing relevant beta-1 adrenergic receptor (ADRB1) polymorphisms and recent beta-blocker studies. Through this, we will understand how bucindolol may help patients with atrial fibrillation and heart failure with reduced ejection fraction (AF-HFrEF), which carries poor prognosis. RECENT FINDINGS: Retrospective study of the...
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