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Article

Blocking Palmitoylation of Toxoplasma gondii Myosin Light Chain 1 Disrupts Glideosome Composition but Has Little Impact on Parasite Motility.

mSphere - 19 May 2021

Rompikuntal Pramod K, Kent Robyn S, Foe Ian T, Deng Bin, Bogyo Matthew, Ward Gary E

Abstract excerpt

Toxoplasma gondii is a widespread apicomplexan parasite that causes severe disease in immunocompromised individuals and the developing fetus. Like other apicomplexans, T. gondii uses an unusual form of substrate-dependent gliding motility to invade cells of its hosts and to disseminate throughout the body during infection. It is well established that a myosin motor consisting of a class XIVa heavy chain (TgMyoA)...

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Identifiers

PMID: 34011689
DOI: 10.1128/mSphere.00823-20
PMCID: PMC8265671

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Blocking Palmitoylation of Toxoplasma gondii Myosin Light Chain 1 Disrupts Glideosome Composition but Has Little Impact on Parasite Motility.PMID 34011689Read ↗

Blocking palmitoylation of <i>Toxoplasma gondii</i> myosin light chain 1 disrupts glideosome composition but has little impact on parasite motilitySemantic proximity Read ↗

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