Article
Prevalence of COMT Val158Met polymorphism in Eastern UP population.
Cellular and molecular biology (Noisy-le-Grand, France) - 31 Jul 2017
Kumar P, Yadav U, Rai V
Abstract excerpt
Catechol-O-methyltransferase (COMT) is an abundant S-adenosylmethionine (SAM-)-dependent methyltransferase that methylates catechol compounds, including catecholamines and catecholestrogens.COMT gene located at chromosome 22q11.2 contains a functional polymorphism at codon 158(Val158Met), which has been related to psychiatric diseases and different types of cancer. COMT might affect tHcy levels because as a...
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