Article
Loss of end-differentiated β-cell phenotype following pancreatic islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Mar 2018
Anderson S J, White M G, Armour S L, Maheshwari R, Tiniakos D, Muller Y D, Berishvili E, Berney T, Shaw J A M
Abstract excerpt
Replacement of pancreatic β-cells through deceased donor islet transplantation is a proven therapy for preventing recurrent life-threatening hypoglycemia in type 1 diabetes. Although near-normal glucose levels and insulin independence can be maintained for many years following successful islet transplantation, restoration of normal functional β-cell mass has remained elusive. It has recently been proposed that...
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