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Article

Canonical and Non-Canonical Autophagy in HIV-1 Replication Cycle

23 Sept 2017

Abstract excerpt

Autophagy is a lysosomal-dependent degradative process essential for maintaining cellular homeostasis, and is a key player in innate and adaptive immune responses to intracellular pathogens such as human immunodeficiency virus type 1 (HIV-1). In HIV-1 target cells, autophagy mechanisms can (i) selectively direct viral proteins and viruses for degradation; (ii) participate in the processing and presentation of...

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PMID: 28946621
DOI: 10.3390/v9100270

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