Autophagy Restricts HIV-1 Infection by Selectively Degrading Tat in CD4 ⁺ T Lymphocytes

Abstract excerpt

UNLABELLED: Autophagy is a ubiquitous mechanism involved in the lysosomal-mediated degradation of cellular components when they are engulfed in vacuoles called autophagosomes. Autophagy is also recognized as an important regulator of the innate and adaptive immune responses against numerous pathogens, which have, therefore, developed strategies to block or use the autophagy machinery to their own benefit. Upon...

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