Article
Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis.
PLoS pathogens - 1 Jun 2024
Tseng Kuo-Yao, Huang Yu-Tsung, Huang Yu-Ting, Su Yu-Ting, Wang An-Ni, Weng Wen-Yen, Ke Cai-Ling, Yeh Yu-Chiao, Wang Jhih-Jie, Du Shin-Hei, Gu Zi-Qi, Chen Wei-Lin, Lin Ching-Hsuan, Tsai Yu-Huan
Abstract excerpt
Candida albicans is a leading cause of intravascular catheter-related infections. The capacity for biofilm formation has been proposed to contribute to the persistence of this fungal pathogen on catheter surfaces. While efforts have been devoted to identifying microbial factors that modulate C. albicans biofilm formation in vitro, our understanding of the host factors that may shape C. albicans persistence in...
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