Article
The ENPP1 K121Q polymorphism modulates developing of bone disorders in type 2 diabetes: A cross sectional study.
Gene - 30 Dec 2017
Neamati Nahid, Hosseini Seyed Reza, Hajiahmadi Mahmood, Halalkhor Sohrab, Nooreddini Hajighorban, Niaki Haleh Akhavan, Korani Bahare, Parsian Hadi
Abstract excerpt
BACKGROUND: Osteoporosis and osteopenia are common diseases in every population. Type 2 diabetes mellitus (T2DM) can lead to the development of various complications, such as bone disorders especially among elderly individuals. Studies suggested that ectonucleotide pyrophosphatase/phosphodiesterase1 (ENPP1) is contributed in insulin resistance and also the inhibition of bone mineralization. In this study,...
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