Article
Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017
Karlsen Tine V, Reikvam Tore, Tofteberg Anne, Nikpey Elham, Skogstrand Trude, Wagner Marek, Tenstad Olav, Wiig Helge
Abstract excerpt
OBJECTIVE: Lymphatic vessels play an important role in body fluid, as well as immune system homeostasis. Although the role of malfunctioning or missing lymphatics has been studied extensively, less is known on the functional consequences of a chronically expanded lymphatic network or lymphangiogenesis. APPROACH AND RESULTS: To this end, we used K14-VEGF-C (keratin-14 vascular endothelial growth factor-C)...
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