Article
Clinically significant mutations in HIV-infected patients with lung adenocarcinoma.
British journal of cancer - 24 Oct 2017
Thaler Jonathan, Sigel Carlie, Beasley Mary Beth, Wisnivesky Juan, Crothers Kristina, Bauml Joshua, Hysell Kristen, Emu Brinda, Borsu Laetitia, Sigel Keith
Abstract excerpt
BACKGROUND: Lung cancer is a major cause of death in HIV-infected (HIV+) persons. In this study, we compared the prevalence of tumour EGFR and KRAS mutations in a cohort of lung adenocarcinoma patients by HIV status. METHODS: We collected data from 55 HIV+ patients with lung adenocarcinoma matched to 136 uninfected comparators. We compared the prevalence of EGFR and KRAS mutations by HIV status. We then compared...
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