Article
Metabolic Profiling of Central Nervous System Disease in Trypanosoma brucei rhodesiense Infection.
The Journal of infectious diseases - 5 Dec 2017
Lamour Sabrina D, Alibu Vincent P, Holmes Elaine, Sternberg Jeremy M
Abstract excerpt
Background: The progression of human African trypanosomiasis from the early hemolymphatic stage to the late meningoencephalitic stage is of critical diagnostic importance as it determines the choice of potentially toxic drug regimens. Current diagnostic criteria involving analysis of cerebrospinal fluid (CSF) for parasites and/or pleocytosis are sensitive, but recent evidence suggests that specificity may be...
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