Article
The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia.
Scientific reports - 18 Sept 2017
Ren H Y, Wang Q, Lei W, Zhang C C, Li Y F, Li X J, Li M L, Deng W, Huang C H, Du F, Zhao L S, Wang Y C, Ma X H, Hu X, Li T
Abstract excerpt
Both post-mortem and neuroimaging studies have identified abnormal white matter (WM) microstructure in patients with schizophrenia. However, its genetic underpinnings and relevant biological pathways remain unclear. In order to unravel the genes and the pathways associated with abnormal WM microstructure in schizophrenia, we recruited 100 first-episode, drug-naïve patients with schizophrenia and 140 matched...
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