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MAD2B acts as a negative regulatory partner of TCF4 on proliferation in human dermal papilla cells

11 Sept 2017

Abstract excerpt

Dermal papilla cells (DPCs) are important components of hair follicles and play a critical role in hair follicle development. However, the mechanisms by which DPCs induce hair follicle development remain unclear. In the present study, we identified the mitotic arrest deficient protein MAD2B as a modifier of DPCs. Overexpression of MAD2B inhibited DPC aggregative growth and proliferation induced by the Wnt...

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PMID: 28916740
DOI: 10.1038/s41598-017-10350-w

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