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Article

MicroRNAs as potential targets for progressive pulmonary fibrosis

5 Nov 2015

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and devastating disorder. It is characterized by alveolar epithelial cell injury and activation, infiltration of inflammatory cells, initiation of epithelial mesenchymal transition (EMT), aberrant proliferation and activation of fibroblasts, exaggerated deposition of extracellular matrix (ECM) proteins, and finally leading to the destruction of lung...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 26594173
DOI: 10.3389/fphar.2015.00254

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