Article
Genetics association study and functional analysis on osteoporosis susceptibility gene BDNF.
Yi chuan = Hereditas - 20 Aug 2017
Yang Man, Lu Bing-Jie, Duan Yuan-Yuan, Chen Xiao-Feng, Ma Jian-Gang, Guo Yan
Abstract excerpt
To explore the relationship between brain-derived neurotrophic factor (BDNF) gene and bone mineral density (BMD) in Chinese Han population, we performed association analysis of 14 tag SNPs on BDNF gene with hip/spine BMD in 1300 Han Chinese samples from Shaanxi Province. We found that 8 of the 14 SNPs were significantly associated with hip or spine BMD (P < 0.05). Moreover, the SNP rs16917237 was significantly...
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