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Article

Liquid dynamic medicine and N-of-1 clinical trials: a change of perspective in oncology research.

Journal of experimental & clinical cancer research : CR - 13 Sept 2017

Silvestris Nicola, Ciliberto Gennaro, De Paoli Paolo, Apolone Giovanni, Lavitrano Maria Luisa, Pierotti Marco A, Stanta Giorgio

Abstract excerpt

The increasing use of genomics to define the pattern of actionable mutations and to test and validate new therapies for individual cancer patients, and the growing application of liquid biopsy to dynamically track tumor evolution and to adapt molecularly targeted therapy according to the emergence of tumor clonal variants is shaping modern medical oncology., In order to better describe this new therapeutic...

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Identifiers

PMID: 28903768
DOI: 10.1186/s13046-017-0598-x
PMCID: PMC5598055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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