Article
Diffusion kurtosis imaging evaluating epithelial-mesenchymal transition in colorectal carcinoma xenografts model: a preliminary study.
Scientific reports - 12 Sept 2017
Liu Huanhuan, Shen Wenbin, Zhang Caiyuan, Cui Yanfen, Li Jinning, Zhang Tingting, Chen Weibo, Wang Dengbin
Abstract excerpt
Epithelial-mesenchymal transition (EMT) plays an important role in aggravating invasiveness and metastatic behavior of colorectal cancer (CRC). Identification of EMT is important for structuring treatment strategy, but has not yet been studied by using noninvasive imaging modality. Diffusion kurtosis imaging (DKI) is an advanced diffusion weighted model that could reflect tissue microstructural changes in vivo....
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