Article
In vivo molecular profiling of human glioma using diffusion kurtosis imaging.
Journal of neuro-oncology - 1 Jan 2017
Hempel Johann-Martin, Bisdas Sotirios, Schittenhelm Jens, Brendle Cornelia, Bender Benjamin, Wassmann Henk, Skardelly Marco, Tabatabai Ghazaleh, Vega Salvador Castaneda, Ernemann Ulrike, Klose Uwe
Abstract excerpt
The purpose of this study is to assess the diagnostic performance of diffusion kurtosis imaging (DKI) for in vivo molecular profiling of human glioma. Normalized mean kurtosis (MKn) and mean diffusivity (MDn) metrics from DKI were assessed in 50 patients with histopathologically confirmed glioma. The results were compared in regard to the WHO-based histological findings and molecular characteristics leading to...
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