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Primary ciliary dyskinesia ciliated airway cells show increased susceptibility toHaemophilus influenzaebiofilm formation

1 Sept 2017

Abstract excerpt

(NTHi) is the most common pathogen in primary ciliary dyskinesia (PCD) patients. We hypothesised that abnormal ciliary motility and low airway nitric oxide (NO) levels on airway epithelial cells from PCD patients might be permissive for NTHi colonisation and biofilm development.We used a primary epithelial cell co-culture model to investigate NTHi infection. Primary airway epithelial cells from PCD and non-PCD...

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PMID: 28890436
DOI: 10.1183/13993003.00612-2017

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