Article
Ciliated air-liquid cultures as an aid to diagnostic testing of primary ciliary dyskinesia.
Chest - 1 Dec 2010
Hirst Robert A, Rutman Andrew, Williams Gwyneth, O'Callaghan Chris
Abstract excerpt
BACKGROUND: The diagnosis of primary ciliary dyskinesia (PCD) can prove difficult because of secondary damage of ciliated tissue. METHODS: Here we audit culturing cells, obtained by nasal brushing, to a ciliated phenotype using an air-liquid interface method to determine if the effects of secondary damage on cilia were reduced following culture. RESULTS: Of 231 patients consecutively referred for diagnostic...
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